|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CD289
Toll-like receptor 9
Toll/interleukin-1 receptor-like protein 9
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:systemic_lupus_erythematosus
asthma
autoimmune diseases
inflammatory diseases
rheumatoid arthritis
|
|
gptkbp:discoveredBy
|
Shizuo Akira
|
|
gptkbp:encodes
|
Toll-like receptor 9
|
|
gptkbp:Entrez_Gene_ID
|
54106
ENSG00000136869
|
|
gptkbp:expressedIn
|
gptkb:B_cells
gptkb:plasmacytoid_dendritic_cells
|
|
gptkbp:firstDescribed
|
2000
|
|
gptkbp:function
|
activation of innate immune response
recognition of unmethylated CpG DNA
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
11850
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TLR9 gene
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_3
3p21.3
|
|
gptkbp:mutationAssociatedWith
|
increased susceptibility to infection
altered immune response
|
|
gptkbp:OMIM
|
605474
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse
right
|
|
gptkbp:pathway
|
gptkb:Toll-like_receptor_signaling_pathway
NF-kappa B signaling pathway
|
|
gptkbp:product
|
TLR9 protein
|
|
gptkbp:proteinFamily
|
gptkb:Toll-like_receptor_family
leucine-rich repeat
TIR domain
|
|
gptkbp:regulates
|
gptkb:insulin
cytokines
|
|
gptkbp:target
|
immunotherapy
vaccine adjuvants
|
|
gptkbp:UniProtID
|
gptkb:Q9NR96
|
|
gptkbp:bfsParent
|
gptkb:CD289
gptkb:TLR9
|
|
gptkbp:bfsLayer
|
8
|