TLR6

GPTKB entity

Statements (47)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:activatesPathway gptkb:NF-kappaB_signaling_pathway
gptkbp:alias gptkb:CD286
Toll/interleukin-1 receptor-like protein 2
gptkbp:alternativeSplicing yes
gptkbp:associatedWith asthma
autoimmune diseases
inflammatory response
allergic diseases
gptkbp:component integral component of membrane
gptkbp:discoveredIn 2001
gptkbp:encodedBy TLR6 gene
gptkbp:Entrez_Gene_ID 10333
ENSG00000135048
gptkbp:expressedIn dendritic cells
macrophages
immune cells
monocytes
gptkbp:formsHeterodimerWith gptkb:TLR2
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:fullName Toll-like receptor 6
gptkbp:function innate immune response
transmembrane signaling receptor activity
pattern recognition receptor
gptkbp:geneType protein-coding
gptkbp:GOProcess immune system process
gptkbp:HGNC_ID 11851
https://www.w3.org/2000/01/rdf-schema#label TLR6
gptkbp:length 796 amino acids
gptkbp:locatedOnChromosome gptkb:chromosome_4
4p14
gptkbp:location gptkb:cell_membrane
gptkbp:memberOf gptkb:Toll-like_receptor_family
gptkbp:molecularWeight approximately 90 kDa
gptkbp:OMIM 605403
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Rattus_norvegicus
gptkbp:PDB 5EP4
gptkbp:recognizedBy bacterial lipoproteins
diacyl lipopeptides
gptkbp:RefSeq NM_006068
gptkbp:relatedTo gptkb:TLR1
gptkb:TLR10
gptkbp:UniProtID Q9Y2C9
gptkbp:bfsParent gptkb:Toll-like_receptors
gptkbp:bfsLayer 7