Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:NF-kB_pathway
|
| gptkbp:alsoKnownAs |
gptkb:TLR4
|
| gptkbp:associatedWith |
sepsis
inflammatory diseases |
| gptkbp:binds |
lipopolysaccharide
|
| gptkbp:discoveredIn |
1997
|
| gptkbp:encodedBy |
gptkb:TLR4_gene
|
| gptkbp:expressedIn |
dendritic cells
macrophages monocytes |
| gptkbp:formsComplexWith |
gptkb:CD14
gptkb:MD-2 |
| gptkbp:foundIn |
humans
mice |
| gptkbp:function |
innate immune response
pattern recognition receptor |
| https://www.w3.org/2000/01/rdf-schema#label |
CD286
|
| gptkbp:locatedOnChromosome |
chromosome 9q32-q33 (human)
|
| gptkbp:structure |
transmembrane protein
|
| gptkbp:UniProtID |
O00206
|
| gptkbp:bfsParent |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
| gptkbp:bfsLayer |
7
|