TIM barrel

URI: https://gptkb.org/entity/TIM_barrel

GPTKB entity

Statements (49)

Predicate	Object
gptkbp:instanceOf	protein fold
gptkbp:alphaHelicesSurround	beta barrel
gptkbp:alsoKnownAs	(β/α)8 barrel
gptkbp:betaStrandsForm	closed barrel
gptkbp:commonIn	metabolic enzymes
gptkbp:example	gptkb:phosphoserine_aminotransferase gptkb:pyruvate_kinase gptkb:aldolase gptkb:glyceraldehyde-3-phosphate_dehydrogenase gptkb:phosphoglycerate_kinase gptkb:phosphoglucose_isomerase gptkb:phosphoglucomutase gptkb:enolase gptkb:phosphoglycerate_mutase gptkb:phosphoenolpyruvate_carboxykinase gptkb:glucose-6-phosphate_isomerase gptkb:indole-3-glycerol-phosphate_synthase gptkb:mannose-6-phosphate_isomerase gptkb:methylmalonyl-CoA_mutase gptkb:orotidine_5'-phosphate_decarboxylase gptkb:phosphomannose_isomerase gptkb:phosphoribosyl_pyrophosphate_synthetase gptkb:phosphoribosylanthranilate_isomerase gptkb:phosphoribosyltransferase gptkb:phosphoserine_phosphatase gptkb:phosphotriesterase gptkb:phosphotungstate_aminotransferase gptkb:phosphotungstate_carboxykinase gptkb:phosphotungstate_dehydrogenase gptkb:phosphotungstate_isomerase gptkb:phosphotungstate_kinase gptkb:phosphotungstate_mutase gptkb:phosphotungstate_oxidase gptkb:phosphotungstate_phosphatase gptkb:phosphotungstate_pyrophosphate_synthetase gptkb:phosphotungstate_reductase gptkb:phosphotungstate_synthase gptkb:phosphotungstate_transferase gptkb:ribulose-phosphate_3-epimerase gptkb:triosephosphate_isomerase
gptkbp:firstDescribed	1976
gptkbp:foundIn	many enzymes
https://www.w3.org/2000/01/rdf-schema#label	TIM barrel
gptkbp:namedAfter	gptkb:triosephosphate_isomerase
gptkbp:structure	eight alpha helices and eight parallel beta strands
gptkbp:bfsParent	gptkb:triose_phosphate_isomerase gptkb:Alpha_and_beta_proteins_(a/b) gptkb:enolase
gptkbp:bfsLayer	7