glucose-6-phosphate isomerase

URI: https://gptkb.org/entity/glucose-6-phosphate_isomerase
GPTKB entity
Statements (38)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:activeSiteResidue glutamate
lysine
histidine
gptkbp:alternativeName gptkb:phosphoglucose_isomerase
autocrine motility factor
maturation factor
neuroleukin
phosphohexose isomerase
gptkbp:catalyzes isomerization of glucose-6-phosphate to fructose-6-phosphate
gptkbp:cofactor none
gptkbp:deficiencyCauses gptkb:nonspherocytic_hemolytic_anemia
gptkbp:discoveredBy 1930s
gptkbp:EC_number 5.3.1.9
gptkbp:enzymeClassification gptkb:isomerase
gptkbp:foundIn gptkb:cytoplasm
gptkbp:gene gptkb:GPI
gptkbp:GO_term GO:0004347
https://www.w3.org/2000/01/rdf-schema#label glucose-6-phosphate isomerase
gptkbp:involves glycolysis
gluconeogenesis
gptkbp:locatedOnChromosome 19q13.11
gptkbp:molecularWeight ~63 kDa
gptkbp:OMIM 172400
gptkbp:PDB 1IRI
gptkbp:presentIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:RefSeq NP_000166.1
gptkbp:structure homodimer
gptkbp:UniProtID P06744
gptkbp:bfsParent gptkb:Autocrine_motility_factor
gptkb:Neuroleukin
gptkb:Phosphoglucose_isomerase
gptkb:GLCP
gptkb:phosphoglucose_isomerase
gptkb:TIM_barrel
gptkbp:bfsLayer 8