phosphoribosyl pyrophosphate synthetase
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:catalyzes |
synthesis of phosphoribosyl pyrophosphate (PRPP)
|
| gptkbp:cofactor |
Mg2+
|
| gptkbp:EC_number |
2.7.6.1
|
| gptkbp:foundIn |
gptkb:Bacteria
archaea eukaryotes |
| gptkbp:gene |
PRPS1
PRPS2 |
| https://www.w3.org/2000/01/rdf-schema#label |
phosphoribosyl pyrophosphate synthetase
|
| gptkbp:involves |
nucleotide biosynthesis
histidine biosynthesis tryptophan biosynthesis |
| gptkbp:mutationAssociatedWith |
gout
Arts syndrome Charcot-Marie-Tooth disease type 5 |
| gptkbp:product |
gptkb:AMP
diphosphate phosphoribosyl pyrophosphate (PRPP) |
| gptkbp:substrate |
gptkb:ATP
ribose 5-phosphate |
| gptkbp:bfsParent |
gptkb:TIM_barrel
|
| gptkbp:bfsLayer |
8
|