triosephosphate isomerase

URI: https://gptkb.org/entity/triosephosphate_isomerase

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:enzyme
gptkbp:alternativeName	gptkb:TIM phosphotriose isomerase triose-phosphate isomerase
gptkbp:associatedWith	gptkb:triosephosphate_isomerase_deficiency
gptkbp:biologicalProcess	isomerase activity
gptkbp:catalyzes	interconversion of dihydroxyacetone phosphate and glyceraldehyde 3-phosphate
gptkbp:cofactor	none
gptkbp:discoveredBy	gptkb:Jakub_Karol_Parnas
gptkbp:EC_number	5.3.1.1
gptkbp:enzymeClassification	gptkb:isomerase
gptkbp:first_structure_solved	1975
gptkbp:foldable	gptkb:TIM_barrel
gptkbp:foundIn	gptkb:gluconeogenesis_pathway gptkb:glycolysis_pathway
gptkbp:gene	gptkb:TPI1
gptkbp:gene_location_(human)	gptkb:chromosome_12p13
gptkbp:inhibitedBy	phosphoglycolohydroxamate
gptkbp:location	gptkb:cytoplasm
gptkbp:molecularWeight	~27 kDa
gptkbp:organism	gptkb:Homo_sapiens gptkb:Bacteria
gptkbp:PDB	gptkb:1TIM
gptkbp:product	gptkb:glyceraldehyde_3-phosphate dihydroxyacetone phosphate
gptkbp:requires	energy production
gptkbp:structure	homodimer
gptkbp:substrate	gptkb:glyceraldehyde_3-phosphate dihydroxyacetone phosphate
gptkbp:UniProtID	gptkb:P60174
gptkbp:bfsParent	gptkb:TIM_barrel
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	triosephosphate isomerase