triose phosphate isomerase

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:enzyme
gptkbp:activeSiteResidue	Glu165 His95
gptkbp:alternativeName	gptkb:TPI gptkb:TIM
gptkbp:associatedWith	gptkb:anemia
gptkbp:biologicalProcess	isomerase activity
gptkbp:catalyzes	interconversion of dihydroxyacetone phosphate and glyceraldehyde 3-phosphate
gptkbp:cofactor	none
gptkbp:deficiencyCauses	gptkb:triosephosphate_isomerase_deficiency
gptkbp:discoveredBy	1930s
gptkbp:EC_number	5.3.1.1
gptkbp:enzyme_commission_class	gptkb:isomerase
gptkbp:enzyme_mechanism	proceeds via enediol intermediate
gptkbp:first_structure_solved	1975
gptkbp:foldable	gptkb:TIM_barrel
gptkbp:foundIn	gptkb:gluconeogenesis_pathway gptkb:glycolysis_pathway
gptkbp:gene	gptkb:TPI1
gptkbp:gene_location_(human)	gptkb:chromosome_12p13
gptkbp:inhibitedBy	phosphoglycolohydroxamate
gptkbp:molecularWeight	27 kDa
gptkbp:organism	present in all domains of life
gptkbp:PDB	gptkb:1TIM
gptkbp:requires	energy metabolism
gptkbp:structure	homodimer
gptkbp:subcellularLocation	gptkb:cytoplasm
gptkbp:UniProtID	gptkb:P60174
gptkbp:bfsParent	gptkb:Calvin_cycle
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	triose phosphate isomerase