TGF-beta type II receptor

URI: https://gptkb.org/entity/TGF-beta_type_II_receptor

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:TGFBR2 Transforming growth factor beta receptor II
gptkbp:associatedWith	gptkb:hereditary_nonpolyposis_colorectal_cancer gptkb:Marfan_syndrome
gptkbp:biologicalProcess	protein serine/threonine kinase activity receptor activity
gptkbp:Entrez_Gene_ID	ENSG00000163513
gptkbp:formsComplexWith	gptkb:TGF-beta_type_I_receptor
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	binds TGF-beta ligands serine/threonine kinase receptor
gptkbp:gene	gptkb:TGFBR2
gptkbp:GO_term	gptkb:GO:0005024
gptkbp:HGNC_ID	11773
gptkbp:interactsWith	gptkb:TGF-beta1 gptkb:TGF-beta2 gptkb:TGF-beta3
gptkbp:involves	gptkb:TGF-beta_signaling_pathway
gptkbp:length	567
gptkbp:locatedOnChromosome	3p24.1
gptkbp:location	gptkb:plasma_membrane
gptkbp:mutationAssociatedWith	cancer predisposition
gptkbp:OMIM	190182
gptkbp:phosphorylates	gptkb:TGF-beta_type_I_receptor
gptkbp:proteinFamily	gptkb:TGF-beta_receptor_family
gptkbp:RefSeq	NP_003233.4
gptkbp:structure	single-pass type I membrane protein
gptkbp:UniProtID	P37173
gptkbp:bfsParent	gptkb:TGF-beta_receptor_family
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	TGF-beta type II receptor