TGF-beta type II receptor

URI: https://gptkb.org/entity/TGF-beta_type_II_receptor
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:TGFBR2
Transforming growth factor beta receptor II
gptkbp:associatedWith gptkb:hereditary_nonpolyposis_colorectal_cancer
gptkb:Marfan_syndrome
gptkbp:biologicalProcess protein serine/threonine kinase activity
receptor activity
gptkbp:Entrez_Gene_ID ENSG00000163513
gptkbp:formsComplexWith gptkb:TGF-beta_type_I_receptor
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function binds TGF-beta ligands
serine/threonine kinase receptor
gptkbp:gene gptkb:TGFBR2
gptkbp:GO_term gptkb:GO:0005024
gptkbp:HGNC_ID 11773
https://www.w3.org/2000/01/rdf-schema#label TGF-beta type II receptor
gptkbp:interactsWith gptkb:TGF-beta1
gptkb:TGF-beta2
gptkb:TGF-beta3
gptkbp:involves gptkb:TGF-beta_signaling_pathway
gptkbp:length 567
gptkbp:locatedOnChromosome 3p24.1
gptkbp:location gptkb:plasma_membrane
gptkbp:mutationAssociatedWith cancer predisposition
gptkbp:OMIM 190182
gptkbp:phosphorylates gptkb:TGF-beta_type_I_receptor
gptkbp:proteinFamily gptkb:TGF-beta_receptor_family
gptkbp:RefSeq NP_003233.4
gptkbp:structure single-pass type I membrane protein
gptkbp:UniProtID P37173
gptkbp:bfsParent gptkb:TGF-beta_receptor_family
gptkbp:bfsLayer 7