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gptkbp:instanceOf
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gptkb:transcription_factor
gptkb:protein
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gptkbp:alternativeName
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gptkb:SP1
Specificity protein 1
Transcription factor Sp1
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gptkbp:associatedWith
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gptkb:Alzheimer's_disease
gptkb:cancer
gptkb:diabetes
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gptkbp:discoveredBy
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1983
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gptkbp:DNA_binding_domain
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zinc finger
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gptkbp:Entrez_Gene_ID
|
6667
ENSG00000185591
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gptkbp:expressedIn
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most tissues
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gptkbp:function
|
regulation of gene expression
binds GC-rich motifs
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gptkbp:gene
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gptkb:SP1
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gptkbp:homologs_in
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gptkb:mouse
gptkb:right
gptkb:zebrafish
gptkb:Drosophila_melanogaster
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gptkbp:interactsWith
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gptkb:CBP/p300
gptkb:TATA-binding_protein
gptkb:c-Myc
gptkb:E2F1
gptkb:HDAC1
gptkb:p53
gptkb:NF-κB
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gptkbp:locatedOnChromosome
|
12q13.1
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gptkbp:molecularWeight
|
~81 kDa
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:PDB
|
1SP1
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gptkbp:postTranslationalModification
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phosphorylation
glycosylation
sumoylation
acetylation
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gptkbp:regulates
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methylation
oxidative stress
ubiquitination
housekeeping genes
apoptosis genes
cell cycle genes
proteasomal degradation
immune response genes
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gptkbp:UniProtID
|
P08047
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gptkbp:bfsParent
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gptkb:SP1_gene
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gptkbp:bfsLayer
|
8
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https://www.w3.org/2000/01/rdf-schema#label
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Sp1 transcription factor
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