gptkbp:instanceOf
|
gptkb:protein
transcription factor
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gptkbp:alternativeName
|
gptkb:SP1
Specificity protein 1
Transcription factor Sp1
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
gptkb:diabetes
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gptkbp:discoveredBy
|
1983
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gptkbp:DNA_binding_domain
|
zinc finger
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gptkbp:Entrez_Gene_ID
|
6667
ENSG00000185591
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gptkbp:expressedIn
|
most tissues
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gptkbp:function
|
regulation of gene expression
binds GC-rich motifs
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gptkbp:gene
|
gptkb:SP1
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gptkbp:homologs_in
|
gptkb:mouse
gptkb:zebrafish
gptkb:Drosophila_melanogaster
right
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sp1 transcription factor
|
gptkbp:interactsWith
|
gptkb:CBP/p300
gptkb:TATA-binding_protein
gptkb:c-Myc
gptkb:E2F1
gptkb:HDAC1
gptkb:p53
gptkb:NF-κB
|
gptkbp:locatedOnChromosome
|
12q13.1
|
gptkbp:molecularWeight
|
~81 kDa
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
gptkbp:PDB
|
1SP1
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
sumoylation
acetylation
|
gptkbp:regulates
|
methylation
oxidative stress
ubiquitination
housekeeping genes
apoptosis genes
cell cycle genes
proteasomal degradation
immune response genes
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gptkbp:UniProtID
|
P08047
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gptkbp:bfsParent
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gptkb:SP1_gene
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gptkbp:bfsLayer
|
8
|