|
gptkbp:instanceOf
|
gptkb:protein
transcription factor
|
|
gptkbp:alias
|
gptkb:TFIID_subunit_A
gptkb:TBP
|
|
gptkbp:binds
|
gptkb:TATA_box
|
|
gptkbp:compatibleWith
|
gptkb:Bacteria
|
|
gptkbp:component
|
gptkb:SL1_complex
gptkb:TFIID_complex
gptkb:TFIIIB_complex
|
|
gptkbp:conservedIn
|
archaea
eukaryotes
|
|
gptkbp:discoveredBy
|
gptkb:James_T._Kadonaga
gptkb:Robert_Tjian
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:domain
|
gptkb:TBP_domain
|
|
gptkbp:encodedBy
|
gptkb:TBP_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000112592
|
|
gptkbp:family
|
gptkb:TBP_family
|
|
gptkbp:function
|
binds TATA box DNA sequence
initiates transcription
|
|
gptkbp:GO
|
GO:0003700
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TATA-binding protein
|
|
gptkbp:interactsWith
|
gptkb:TAFs
gptkb:TFIIA
gptkb:TFIIB
gptkb:BRF1
gptkb:BTAF1
|
|
gptkbp:length
|
339 amino acids (human)
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6q27_(human)
|
|
gptkbp:molecularWeight
|
~38 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:spinocerebellar_ataxia_17
neurological disorders
|
|
gptkbp:OMIM
|
600075
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1CDW
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:RefSeq
|
gptkb:NM_003194
|
|
gptkbp:requires
|
transcription by RNA polymerase I
transcription by RNA polymerase II
transcription by RNA polymerase III
|
|
gptkbp:role
|
promoter recognition
general transcription factor
recruitment of RNA polymerase II
|
|
gptkbp:structure
|
saddle-shaped
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:symbol
|
gptkb:TBP
|
|
gptkbp:UniProtID
|
gptkb:P20226
|
|
gptkbp:bfsParent
|
gptkb:TBP
|
|
gptkbp:bfsLayer
|
6
|