Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:activatedBy |
Hedgehog ligand
|
| gptkbp:alternativeName |
gptkb:SMO
G protein-coupled receptor SMO Smoothened homolog |
| gptkbp:associatedWith |
gptkb:medulloblastoma
basal cell carcinoma |
| gptkbp:biologicalProcess |
G protein-coupled receptor activity
|
| gptkbp:cellularComponent |
gptkb:cell_membrane
|
| gptkbp:encodedBy |
SMO gene
|
| gptkbp:Entrez_Gene_ID |
6608
ENSG00000128602 |
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:function |
gptkb:Hedgehog_signaling_pathway
signal transduction |
| gptkbp:HGNC_ID |
HGNC:11119
|
| https://www.w3.org/2000/01/rdf-schema#label |
Smoothened (SMO)
|
| gptkbp:inhibitedBy |
gptkb:sonidegib
gptkb:vismodegib gptkb:cyclopamine |
| gptkbp:length |
787 amino acids
|
| gptkbp:locatedOnChromosome |
7q32.1
|
| gptkbp:orthologIn |
Smo (Drosophila melanogaster)
|
| gptkbp:regulates |
gptkb:GLI_transcription_factors
|
| gptkbp:UniProtID |
Q99835
|
| gptkbp:bfsParent |
gptkb:PTCH1
gptkb:SHH gptkb:Hedgehog_signaling_pathway |
| gptkbp:bfsLayer |
7
|