cyclopamine

GPTKB entity

Statements (18)
Predicate Object
gptkbp:instanceOf alkaloid
steroidal alkaloid
gptkbp:CASNumber 4449-51-8
gptkbp:category metabolite
plant toxin
teratogen
gptkbp:cause birth defects in sheep
gptkbp:chemicalFormula C27H41NO2
gptkbp:discoveredBy 1960s
gptkbp:foundIn gptkb:Veratrum_californicum
https://www.w3.org/2000/01/rdf-schema#label cyclopamine
gptkbp:inhibitedBy gptkb:Hedgehog_signaling_pathway
gptkbp:IUPACName (2β,3β,4β,16β,17β)-4,17-dimethyl-2,3,16-trihydroxy-5α,6β,14β,15β,16β,17β-hexahydrocyclopenta[a]phenanthridine
gptkbp:molecularWeight 411.62 g/mol
gptkbp:studiedBy cancer biology
gptkbp:target Smoothened protein
gptkbp:bfsParent gptkb:Hedgehog_signaling_pathway
gptkbp:bfsLayer 7