|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:ANOP3
gptkb:MCOPS3
gptkb:SRY-box_transcription_factor_2
|
|
gptkbp:associatedWith
|
gptkb:cancer
eye development
anophthalmia
stem cell self-renewal
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:component
|
gptkb:nucleus
|
|
gptkbp:domain
|
HMG-box domain
|
|
gptkbp:encodedBy
|
gptkb:SOX2_gene
|
|
gptkbp:Entrez_Gene_ID
|
6657
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:testis
brain
esophagus
embryonic stem cells
neural stem cells
eye tissue
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
transcription factor
DNA-binding transcription factor activity
|
|
gptkbp:gene
|
gptkb:SOX2
|
|
gptkbp:GOProcess
|
positive regulation of transcription
stem cell population maintenance
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SOX2 protein
|
|
gptkbp:interactsWith
|
gptkb:KLF4_protein
gptkb:NANOG_protein
gptkb:OCT4_protein
|
|
gptkbp:involvedIn
|
embryonic development
neurogenesis
maintenance of pluripotency
|
|
gptkbp:length
|
317 amino acids
|
|
gptkbp:locale
|
gptkb:nucleus
|
|
gptkbp:locatedOnChromosome
|
gptkb:3q26.3-q27_(human)
|
|
gptkbp:memberOf
|
gptkb:SOX_family
|
|
gptkbp:molecularWeight
|
34 kDa
|
|
gptkbp:mutationAssociatedWith
|
SOX2 anophthalmia syndrome
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
|
|
gptkbp:PDB
|
1GT0
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:regulates
|
gene expression
|
|
gptkbp:UniProtID
|
gptkb:P48431
|
|
gptkbp:bfsParent
|
gptkb:POU5F1_gene
gptkb:SOX2_gene
|
|
gptkbp:bfsLayer
|
7
|