|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:Cdc42Hs
gptkb:Cell_division_control_protein_42_homolog
G25K GTP-binding protein
|
|
gptkbp:associatedWith
|
gptkb:cancer
immunodeficiency
neurodevelopmental disorders
|
|
gptkbp:biologicalProcess
|
GTP binding
GTPase activity
cell division
cellular response to growth factor stimulus
endocytosis
exocytosis
filopodium assembly
|
|
gptkbp:cellularComponent
|
gptkb:Golgi_apparatus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:encodedBy
|
CDC42 gene
|
|
gptkbp:Entrez_Gene_ID
|
998
|
|
gptkbp:enzymeCommissionNumber
|
3.6.5.2
|
|
gptkbp:family
|
Rho family GTPase
|
|
gptkbp:function
|
signal transduction
cell migration
regulation of cell cycle
cell polarity
regulation of actin cytoskeleton
|
|
gptkbp:gene
|
gptkb:CDC42
|
|
gptkbp:HGNC_ID
|
1736
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rho GTPase CDC42
|
|
gptkbp:interactsWith
|
gptkb:PAK1
gptkb:WASP
gptkb:RhoA
gptkb:Rac1
gptkb:IQGAP1
|
|
gptkbp:length
|
191
|
|
gptkbp:locatedOnChromosome
|
1p36.12
|
|
gptkbp:OMIM
|
116952
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Cdc42
|
|
gptkbp:orthologInYeast
|
gptkb:CDC42
|
|
gptkbp:PDB
|
gptkb:1A4R
|
|
gptkbp:postTranslationalModification
|
prenylation
phosphorylation
|
|
gptkbp:regulates
|
activated by GEFs
inactivated by GAPs
regulated by GDIs
|
|
gptkbp:subfamily
|
CDC42 subfamily
|
|
gptkbp:UniProtID
|
gptkb:P60953
|
|
gptkbp:bfsParent
|
gptkb:CDC42
|
|
gptkbp:bfsLayer
|
7
|