|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:activatedBy
|
gptkb:mTORC1
|
|
gptkbp:alias
|
gptkb:GTP-binding_protein_Rheb
gptkb:RHEB2
gptkb:Ras_homolog_enriched_in_brain
|
|
gptkbp:associatedWith
|
gptkb:tuberous_sclerosis
|
|
gptkbp:biologicalProcess
|
cell proliferation
GTP binding
GTPase activity
cell growth
regulation of autophagy
|
|
gptkbp:encodedBy
|
gptkb:RHEB_gene
|
|
gptkbp:Entrez_Gene_ID
|
6009
ENSG00000106615
|
|
gptkbp:family
|
gptkb:Ras_superfamily
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
gptkb:G_protein-coupled_receptor
regulator of mTOR signaling pathway
|
|
gptkbp:gene
|
gptkb:RHEB
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:10021
|
|
gptkbp:inhibitedBy
|
gptkb:TSC1/TSC2_complex
|
|
gptkbp:length
|
184
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7q36.1
|
|
gptkbp:location
|
gptkb:cytoplasm
lysosome membrane
|
|
gptkbp:OMIM
|
605426
|
|
gptkbp:orthologIn
|
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster
|
|
gptkbp:pathway
|
gptkb:mTOR_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
|
|
gptkbp:PDB
|
1XTQ
|
|
gptkbp:postTranslationalModification
|
farnesylation
|
|
gptkbp:structure
|
gptkb:small_GTPase_superfamily
|
|
gptkbp:subfamily
|
gptkb:Rheb_subfamily
|
|
gptkbp:UniProtID
|
Q15382
|
|
gptkbp:bfsParent
|
gptkb:TSC1/TSC2_complex
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rheb GTPase
|