|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:retinoblastoma_1
gptkb:pRb
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Small_Cell_Lung_Cancer
gptkb:bladder_cancer
gptkb:retinoblastoma
osteosarcoma
|
|
gptkbp:discoveredBy
|
gptkb:Alfred_G._Knudson
|
|
gptkbp:encodes
|
gptkb:retinoblastoma_protein
|
|
gptkbp:Entrez_Gene_ID
|
5925
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:firstDescribed
|
1986
|
|
gptkbp:function
|
gptkb:tumor_suppressor
|
|
gptkbp:HGNC_ID
|
9884
|
|
gptkbp:inhibitedBy
|
gptkb:E2F_transcription_factors
|
|
gptkbp:length
|
180 kb
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_13
13q14.2
|
|
gptkbp:mutationAssociatedWith
|
loss-of-function
|
|
gptkbp:numberOfExons
|
27
|
|
gptkbp:OMIM
|
614041
|
|
gptkbp:orthologInMouse
|
gptkb:Rb1
|
|
gptkbp:orthologInZebrafish
|
rb1
|
|
gptkbp:regulates
|
cell cycle
|
|
gptkbp:symbol
|
gptkb:RB1
|
|
gptkbp:UniProtID
|
P06400
|
|
gptkbp:bfsParent
|
gptkb:pRb
gptkb:retinoblastoma-associated_protein
gptkb:retinoblastoma_protein
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RB1 gene
|