Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:retinoblastoma_1
gptkb:pRb |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:retinoblastoma
bladder cancer Small Cell Lung Cancer osteosarcoma |
| gptkbp:discoveredBy |
gptkb:Alfred_G._Knudson
|
| gptkbp:encodes |
gptkb:retinoblastoma_protein
|
| gptkbp:Entrez_Gene_ID |
5925
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:firstDescribed |
1986
|
| gptkbp:function |
tumor suppressor
|
| gptkbp:HGNC_ID |
9884
|
| https://www.w3.org/2000/01/rdf-schema#label |
RB1 gene
|
| gptkbp:inhibitedBy |
gptkb:E2F_transcription_factors
|
| gptkbp:length |
180 kb
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_13
13q14.2 |
| gptkbp:mutationAssociatedWith |
loss-of-function
|
| gptkbp:numberOfExons |
27
|
| gptkbp:OMIM |
614041
|
| gptkbp:orthologInMouse |
gptkb:Rb1
|
| gptkbp:orthologInZebrafish |
rb1
|
| gptkbp:regulates |
cell cycle
|
| gptkbp:symbol |
gptkb:RB1
|
| gptkbp:UniProtID |
P06400
|
| gptkbp:bfsParent |
gptkb:Rb_protein
gptkb:pRb gptkb:retinoblastoma-associated_protein gptkb:retinoblastoma_protein |
| gptkbp:bfsLayer |
7
|