|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:HePTP
gptkb:LC-PTP
gptkb:hematopoietic_protein_tyrosine_phosphatase
|
|
gptkbp:associatedWith
|
autoimmune diseases (potential association)
|
|
gptkbp:discoveredBy
|
1992
|
|
gptkbp:Entrez_Gene_ID
|
5778
ENSG00000135334
|
|
gptkbp:expressedIn
|
gptkb:T_cells
hematopoietic cells
|
|
gptkbp:fullName
|
gptkb:Protein_Tyrosine_Phosphatase,_Non-Receptor_Type_7
|
|
gptkbp:function
|
signal transduction
protein tyrosine phosphatase activity
negative regulation of MAP kinase activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
gptkb:PTPN7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PTPN7
|
|
gptkbp:interactsWith
|
gptkb:MAP2K1
gptkb:MAPK1
gptkb:MAPK3
|
|
gptkbp:locatedOnChromosome
|
1
|
|
gptkbp:location
|
1q32.1
|
|
gptkbp:molecularWeight
|
38 kDa
|
|
gptkbp:numberOfExons
|
8
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Ptpn7
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
|
|
gptkbp:PDB
|
1ZC0
2A8B
|
|
gptkbp:phosphatase_domain
|
present
|
|
gptkbp:proteinFamily
|
gptkb:protein_tyrosine_phosphatase_family
non-receptor type PTPs
|
|
gptkbp:regulates
|
immune response
T cell activation
|
|
gptkbp:reviewedBy
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:HGNC
gptkb:UniProt
gptkb:Ensembl
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q06124
|
|
gptkbp:bfsParent
|
gptkb:protein_tyrosine_phosphatases
|
|
gptkbp:bfsLayer
|
6
|