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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
Polycomb complex 1
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gptkbp:amendedBy
|
gptkb:histone_H2A
|
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gptkbp:associatedWith
|
gptkb:Polycomb_group_proteins
|
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gptkbp:biologicalProcess
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histone modification
epigenetic regulation
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gptkbp:catalyzes
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monoubiquitination of histone H2A at lysine 119
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gptkbp:component
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gptkb:PCGF_proteins
gptkb:CBX_proteins
gptkb:PHC_proteins
gptkb:RING1A
gptkb:RING1B
BMI1
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gptkbp:discoveredIn
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gptkb:Drosophila_melanogaster
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gptkbp:fullName
|
gptkb:Polycomb_Repressive_Complex_1
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gptkbp:function
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gene silencing
chromatin modification
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gptkbp:GO_term
|
GO:0035102
Polycomb group (PcG) protein complex
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https://www.w3.org/2000/01/rdf-schema#label
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PRC1 complex
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gptkbp:inhibitedBy
|
transcription
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gptkbp:interactsWith
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gptkb:RNA_polymerase_II
gptkb:gene
chromatin
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gptkbp:involvedIn
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cancer progression
cell fate determination
stem cell maintenance
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gptkbp:locale
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gptkb:nucleus
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gptkbp:orthologIn
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gptkb:human
gptkb:mouse
gptkb:zebrafish
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gptkbp:regulates
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gptkb:HOX_gene_clusters
developmental genes
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gptkbp:relatedTo
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gptkb:PRC2_complex
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gptkbp:subunit
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gptkb:CBX2
gptkb:CBX4
gptkb:CBX6
gptkb:CBX7
gptkb:CBX8
gptkb:PHC1
gptkb:PHC2
gptkb:PHC3
gptkb:RING1A
gptkb:RING1B
BMI1
PCGF1
RYBP
MBLR
MEL18
NSPC1
PCGF2
PCGF3
PCGF4
PCGF5
PCGF6
YAF2
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gptkbp:bfsParent
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gptkb:CBX_proteins
gptkb:PHC_proteins
gptkb:Polycomb_Repressive_Complex_1
gptkb:Polycomb_Repressive_Complex_1_(PRC1)
gptkb:Polycomb_group_(PcG)_pathway
gptkb:Polyhomeotic_(Ph)
gptkb:RING1A
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gptkbp:bfsLayer
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8
|