Polycomb group (PcG) pathway
GPTKB entity
Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:amendedBy |
chromatin structure
|
| gptkbp:associatedWith |
epigenetic silencing
|
| gptkbp:catalyzes |
H2A ubiquitination
H3K27 methylation |
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
|
| gptkbp:enemyOf |
gptkb:Trithorax_group_(TrxG)_pathway
|
| gptkbp:firstDescribed |
gptkb:Drosophila_melanogaster
|
| gptkbp:foundIn |
eukaryotes
|
| https://www.w3.org/2000/01/rdf-schema#label |
Polycomb group (PcG) pathway
|
| gptkbp:includes |
gptkb:PRC1_complex
gptkb:PRC2_complex |
| gptkbp:involvedIn |
cell fate determination
stem cell maintenance developmental gene regulation |
| gptkbp:involves |
gptkb:Polycomb_group_proteins
|
| gptkbp:medium |
histone modification
|
| gptkbp:regulates |
gene expression
|
| gptkbp:bfsParent |
gptkb:Drosophila_E(z)
|
| gptkbp:bfsLayer |
7
|