Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:p110δ
phosphoinositide 3-kinase delta |
| gptkbp:associatedWith |
gptkb:cancer
immunodeficiency autoimmune disease |
| gptkbp:component |
gptkb:class_IA_PI3K
|
| gptkbp:encodedBy |
gptkb:PIK3CD_gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
|
| gptkbp:function |
involved in signal transduction
regulates immune cell function catalyzes phosphorylation of phosphatidylinositol (4,5)-bisphosphate |
| https://www.w3.org/2000/01/rdf-schema#label |
PI3K delta
|
| gptkbp:inhibitedBy |
gptkb:duvelisib
gptkb:idelalisib gptkb:umbralisib |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_1p36.2
|
| gptkbp:molecularWeight |
~110 kDa
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:subunit |
gptkb:PI3K_complex
|
| gptkbp:bfsParent |
gptkb:idelalisib
gptkb:class_I_PI3K |
| gptkbp:bfsLayer |
5
|