Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:associatedWith |
gptkb:cancer
immunodeficiency autoimmunity |
| gptkbp:encodedBy |
gptkb:PIK3CD_gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
|
| gptkbp:function |
catalyzes phosphorylation of phosphatidylinositol (4,5)-bisphosphate
involved in immune cell signaling |
| https://www.w3.org/2000/01/rdf-schema#label |
p110δ
|
| gptkbp:inhibitedBy |
gptkb:duvelisib
gptkb:idelalisib gptkb:umbralisib |
| gptkbp:interactsWith |
p85 regulatory subunit
|
| gptkbp:locatedIn |
gptkb:cell_membrane
gptkb:cytoplasm |
| gptkbp:memberOf |
gptkb:phosphoinositide_3-kinase_family
gptkb:class_IA_PI3K |
| gptkbp:molecularWeight |
110 kDa
|
| gptkbp:subunit |
gptkb:PI3Kδ_complex
|
| gptkbp:UniProtID |
O00329
|
| gptkbp:bfsParent |
gptkb:PIK3CD
|
| gptkbp:bfsLayer |
5
|