Statements (25)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:chemical_compound
                                        
                                         gptkb:drug  | 
                            
| gptkbp:approvalYear | 
                                    
                                        
                                            
                                            2021
                                        
                                        
                                         | 
                            
| gptkbp:approvedBy | 
                                    
                                        
                                            gptkb:FDA
                                        
                                         | 
                            
| gptkbp:ATCCode | 
                                    
                                        
                                            
                                            L01EM05
                                        
                                        
                                         | 
                            
| gptkbp:brand | 
                                    
                                        
                                            gptkb:Ukoniq
                                        
                                         | 
                            
| gptkbp:CASNumber | 
                                    
                                        
                                            
                                            1353552-87-6
                                        
                                        
                                         | 
                            
| gptkbp:chemicalFormula | 
                                    
                                        
                                            
                                            C32H32N8O2S
                                        
                                        
                                         | 
                            
| gptkbp:developedBy | 
                                    
                                        
                                            gptkb:TG_Therapeutics
                                        
                                         | 
                            
| gptkbp:legalStatus | 
                                    
                                        
                                            
                                            withdrawn
                                        
                                        
                                         | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            
                                            PI3K delta inhibitor
                                        
                                        
                                         CK1 epsilon inhibitor  | 
                            
| gptkbp:retired | 
                                    
                                        
                                            
                                            safety concerns
                                        
                                        
                                         | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            oral
                                        
                                        
                                         | 
                            
| gptkbp:sideEffect | 
                                    
                                        
                                            
                                            diarrhea
                                        
                                        
                                         infections elevated liver enzymes neutropenia  | 
                            
| gptkbp:usedFor | 
                                    
                                        
                                            
                                            treatment of follicular lymphoma
                                        
                                        
                                         treatment of marginal zone lymphoma  | 
                            
| gptkbp:withdrawn | 
                                    
                                        
                                            
                                            2022
                                        
                                        
                                         true  | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:PIK3CD
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            6
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            umbralisib
                                        
                                        
                                         |