Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
phosphoinositide 3-kinase inhibitor |
| gptkbp:approvalYear |
2018
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
L01EM05
|
| gptkbp:brand |
gptkb:Copiktra
|
| gptkbp:CASNumber |
1201438-56-3
|
| gptkbp:chemicalClass |
quinazoline derivative
|
| gptkbp:developer |
gptkb:Verastem
|
| gptkbp:hasMolecularFormula |
C22H17ClN6O
|
| https://www.w3.org/2000/01/rdf-schema#label |
duvelisib
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
PI3K-delta inhibitor
PI3K-gamma inhibitor |
| gptkbp:pregnancyCategory |
not recommended
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
diarrhea
infections rash hepatotoxicity neutropenia inflammatory bowel disease pneumonitis |
| gptkbp:usedFor |
gptkb:small_lymphocytic_lymphoma
chronic lymphocytic leukemia follicular lymphoma |
| gptkbp:bfsParent |
gptkb:protein
|
| gptkbp:bfsLayer |
4
|