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gptkbp:instanceOf
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gptkb:protein
gptkb:enzyme
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gptkbp:alternativeName
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gptkb:phosphatidylinositol-4,5-bisphosphate_3-kinase_catalytic_subunit_delta_isoform
gptkb:PIK3CD_protein
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gptkbp:associatedWith
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leukemia
chronic lymphocytic leukemia
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gptkbp:biologicalProcess
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signal transduction
regulation of apoptosis
regulation of cell proliferation
T cell activation
kinase activity
ATP binding
B cell development
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gptkbp:catalyzes
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phosphorylation of phosphatidylinositol (4,5)-bisphosphate
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gptkbp:cellularComponent
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gptkb:cytoplasm
gptkb:plasma_membrane
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gptkbp:encodedBy
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gptkb:PIK3CD_gene
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gptkbp:foundIn
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humans
mammals
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gptkbp:hasCatalyticSubunit
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gptkb:p110δ
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gptkbp:hasRegulatorySubunit
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p50
p55
p85
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https://www.w3.org/2000/01/rdf-schema#label
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PI3K-delta
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gptkbp:involvedIn
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cell signaling
immune response
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gptkbp:locatedOnChromosome
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gptkb:1p36.22
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gptkbp:memberOf
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gptkb:phosphoinositide_3-kinase_family
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gptkbp:mutationAssociatedWith
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immunodeficiency
activated PI3K-delta syndrome (APDS)
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gptkbp:overexpressedIn
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gptkb:leukocytes
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gptkbp:produces
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gptkb:phosphatidylinositol_(3,4,5)-trisphosphate
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gptkbp:subunit
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gptkb:class_IA_PI3K_complex
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gptkbp:target
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gptkb:copanlisib
gptkb:duvelisib
gptkb:idelalisib
gptkb:umbralisib
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gptkbp:UniProtID
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O00329
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gptkbp:bfsParent
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gptkb:copanlisib
gptkb:PIK3CD
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gptkbp:bfsLayer
|
5
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