Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:phosphatidylinositol-4,5-bisphosphate_3-kinase_catalytic_subunit_delta_isoform
gptkb:PI3K_delta |
| gptkbp:associatedWith |
gptkb:immunodeficiency_14
autoimmune diseases |
| gptkbp:biologicalProcess |
kinase activity
|
| gptkbp:component |
gptkb:phosphoinositide_3-kinase_complex
|
| gptkbp:domain |
gptkb:PI3K/PI4K_domain
C2 domain P85-binding domain |
| gptkbp:encodedBy |
gptkb:PIK3CD_gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
|
| gptkbp:function |
catalyzes phosphorylation of phosphatidylinositol-4,5-bisphosphate
involved in PI3K/AKT signaling pathway |
| gptkbp:locatedOnChromosome |
gptkb:1p36.22
|
| gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:target |
gptkb:idelalisib
|
| gptkbp:UniProtID |
O00329
|
| gptkbp:bfsParent |
gptkb:PI3K-delta
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
PIK3CD protein
|