Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:Ras_protein
gptkb:receptor_tyrosine_kinases |
| gptkbp:associatedWith |
gptkb:cancer
cell survival cell growth insulin signaling |
| gptkbp:catalyzes |
phosphorylation of phosphatidylinositol-4,5-bisphosphate
|
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:hasComponent |
p110 catalytic subunit
p85 regulatory subunit |
| https://www.w3.org/2000/01/rdf-schema#label |
class IA PI3K complex
|
| gptkbp:inhibitedBy |
PI3K inhibitors
|
| gptkbp:involvedIn |
phosphoinositide 3-kinase signaling pathway
|
| gptkbp:produces |
phosphatidylinositol-3,4,5-trisphosphate
|
| gptkbp:subunit |
gptkb:PIK3R1
gptkb:PIK3R2 gptkb:PIK3R3 gptkb:PIK3CA gptkb:PIK3CB gptkb:PIK3CD |
| gptkbp:bfsParent |
gptkb:PI3K-delta
|
| gptkbp:bfsLayer |
6
|