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gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:PIK3CD
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
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gptkbp:associatedWith
|
gptkb:immunodeficiency_14
leukemia
chronic lymphocytic leukemia
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gptkbp:biologicalProcess
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signal transduction
immune response
kinase activity
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gptkbp:cellularComponent
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gptkb:cytoplasm
gptkb:plasma_membrane
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gptkbp:encodedBy
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gptkb:PIK3CD_gene
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gptkbp:enzymeCommissionNumber
|
2.7.1.153
|
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gptkbp:expressedIn
|
gptkb:leukocytes
gptkb:B_cells
gptkb:T_cells
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gptkbp:foundIn
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gptkb:Mus_musculus
gptkb:Homo_sapiens
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gptkbp:hasIsoform
|
gptkb:p110δ
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PI3-kinase p110 delta
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gptkbp:inhibitedBy
|
gptkb:duvelisib
gptkb:idelalisib
gptkb:umbralisib
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gptkbp:locatedOnChromosome
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gptkb:1p36.22
|
|
gptkbp:molecularWeight
|
119 kDa
|
|
gptkbp:partOf
|
gptkb:phosphoinositide_3-kinase_complex
|
|
gptkbp:regulates
|
cell proliferation
cell survival
cell migration
inflammatory response
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gptkbp:UniProtID
|
O00329
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gptkbp:bfsParent
|
gptkb:phosphatidylinositol-4,5-bisphosphate_3-kinase_catalytic_subunit_delta_isoform
gptkb:Phosphatidylinositol_4,5-bisphosphate_3-kinase_catalytic_subunit_delta_isoform
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gptkbp:bfsLayer
|
6
|