Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
Phosphodiesterase family
|
| gptkbp:function |
hydrolyzes phosphodiester bonds
|
| gptkbp:hasBiologicalActivity |
regulation of cyclic nucleotide signaling
|
| https://www.w3.org/2000/01/rdf-schema#label |
PDE family
|
| gptkbp:inhibitedBy |
gptkb:theophylline
gptkb:sildenafil gptkb:rolipram |
| gptkbp:member |
gptkb:PDE1
gptkb:PDE10 gptkb:PDE11 gptkb:PDE2 gptkb:PDE3 gptkb:PDE4 gptkb:PDE5 gptkb:PDE6 gptkb:PDE7 gptkb:PDE8 gptkb:PDE9 |
| gptkbp:proteinFamily |
gptkb:PDE
|
| gptkbp:significance |
target for cardiovascular drugs
target for neurological drugs target for respiratory drugs |
| gptkbp:substrate |
gptkb:cAMP
gptkb:cGMP |
| gptkbp:bfsParent |
gptkb:PDE3
gptkb:Phosphodiesterase |
| gptkbp:bfsLayer |
7
|