Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:Cushing's_disease
adrenal hyperplasia |
| gptkbp:biologicalProcess |
3',5'-cyclic-AMP phosphodiesterase activity
regulation of cAMP signaling |
| gptkbp:enzymeClassification |
EC 3.1.4.53
|
| gptkbp:fullName |
Phosphodiesterase 8
|
| gptkbp:function |
hydrolyzes cAMP
|
| gptkbp:hasIsoform |
PDE8A
PDE8B |
| https://www.w3.org/2000/01/rdf-schema#label |
PDE8
|
| gptkbp:inhibitedBy |
PF-04671536
PF-04957325 |
| gptkbp:locatedOnChromosome |
PDE8A: 15q25; PDE8B: 5q13
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
mouse PDE8
rat PDE8 |
| gptkbp:proteinFamily |
phosphodiesterase
|
| gptkbp:tissue_specificity |
gptkb:adrenal_gland
gptkb:testis brain |
| gptkbp:bfsParent |
gptkb:Cyclic_Phosphodiesterase
|
| gptkbp:bfsLayer |
6
|