Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeSplicing |
produces multiple isoforms
|
| gptkbp:associatedWith |
gptkb:COPD
gptkb:depression inflammatory diseases |
| gptkbp:EC_number |
3.1.4.53
|
| gptkbp:foundIn |
gptkb:human
gptkb:mouse right |
| gptkbp:fullName |
Phosphodiesterase 4
|
| gptkbp:function |
hydrolyzes cAMP
|
| https://www.w3.org/2000/01/rdf-schema#label |
PDE4
|
| gptkbp:inhibitedBy |
gptkb:rolipram
gptkb:roflumilast |
| gptkbp:locatedOnChromosome |
varies by isoform
|
| gptkbp:proteinFamily |
PDE4A
PDE4B PDE4C PDE4D |
| gptkbp:regulates |
intracellular cAMP levels
|
| gptkbp:target |
anti-inflammatory drugs
|
| gptkbp:bfsParent |
gptkb:Cyclic_Phosphodiesterase
|
| gptkbp:bfsLayer |
6
|