Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
cGMP-inhibited phosphodiesterase
|
| gptkbp:associatedWith |
heart failure
thrombosis |
| gptkbp:EC_number |
3.1.4.17
|
| gptkbp:expressedIn |
heart
adipose tissue vascular smooth muscle |
| gptkbp:fullName |
phosphodiesterase 3
|
| gptkbp:function |
hydrolyzes cAMP and cGMP
|
| gptkbp:hasIsoform |
PDE3A
PDE3B |
| https://www.w3.org/2000/01/rdf-schema#label |
PDE3
|
| gptkbp:inhibitedBy |
gptkb:milrinone
cilostazol |
| gptkbp:proteinFamily |
gptkb:PDE_family
|
| gptkbp:regulates |
cardiac contractility
vascular smooth muscle relaxation |
| gptkbp:target |
cardiac drugs
|
| gptkbp:bfsParent |
gptkb:Cyclic_Phosphodiesterase
|
| gptkbp:bfsLayer |
6
|