Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:biologicalProcess |
3',5'-cyclic-AMP phosphodiesterase activity
|
| gptkbp:EC_number |
3.1.4.53
|
| gptkbp:family |
phosphodiesterase family
|
| gptkbp:fullName |
phosphodiesterase 7
|
| gptkbp:function |
hydrolyzes cAMP
|
| gptkbp:gene |
PDE7A
PDE7B |
| gptkbp:GO_term |
GO:0004115
|
| https://www.w3.org/2000/01/rdf-schema#label |
PDE7
|
| gptkbp:inhibitedBy |
BRL-50481
TC3.6 |
| gptkbp:locatedOnChromosome |
6q23.3 (PDE7B)
8q13.1 (PDE7A) |
| gptkbp:role |
neurodegenerative diseases
autoimmune diseases inflammation |
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:substrate |
gptkb:cAMP
|
| gptkbp:tissue_specificity |
gptkb:skeletal_muscle
brain immune cells |
| gptkbp:UniProtID |
Q13946 (PDE7A)
Q9NP56 (PDE7B) |
| gptkbp:bfsParent |
gptkb:Cyclic_Phosphodiesterase
|
| gptkbp:bfsLayer |
6
|