|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:mammalian_target_of_rapamycin
gptkb:mechanistic_target_of_rapamycin
gptkb:FK506-binding_protein_12-rapamycin-associated_protein_1
gptkb:FRAP
RAFT1
RAPT1
|
|
gptkbp:biologicalProcess
|
regulation of cell proliferation
kinase activity
autophagy
regulation of cell growth
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:mTORC2_complex
mTORC1 complex
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000361445
2475
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.1
|
|
gptkbp:fullName
|
gptkb:Serine/threonine-protein_kinase_mTOR
|
|
gptkbp:gene
|
gptkb:MTOR
|
|
gptkbp:hasPfamDomain
|
gptkb:PF00069
PF10409
PF12721
|
|
gptkbp:hasRefSeqID
|
NP_004949.1
|
|
gptkbp:HGNC_ID
|
HGNC:3942
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P49821
|
|
gptkbp:InterPro
|
gptkb:IPR000719
IPR011009
IPR021135
|
|
gptkbp:length
|
2549
|
|
gptkbp:locatedOnChromosome
|
gptkb:1p36.2
|
|
gptkbp:molecularWeight
|
289 kDa
|
|
gptkbp:OMIM
|
601231
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:5FLC
gptkb:6BCU
4JSV
6BCX
6ZWM
|
|
gptkbp:target
|
gptkb:everolimus
gptkb:rapamycin
gptkb:sirolimus
gptkb:temsirolimus
gptkb:torin1
gptkb:PI-103
gptkb:ridaforolimus
AZD2014
AZD8055
BEZ235
BGT226
CC-115
CC-223
GDC-0980
GSK2126458
INK128
KU-0063794
LY3023414
MLN0128
OSI-027
PF-04691502
PP242
TAK-228
WYE-125132
WYE-354
XL388
torkinib
|
|
gptkbp:UniProtID
|
gptkb:P49821
|
|
gptkbp:bfsParent
|
gptkb:NDUFV1
|
|
gptkbp:bfsLayer
|
7
|