Statements (102)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
UniProt accession number
|
| gptkbp:alternativeName |
gptkb:cellular_tumor_antigen_p53
gptkb:BCC7 gptkb:LFS1 gptkb:antigen_NY-CO-13 gptkb:phosphoprotein_p53 gptkb:TRP53 |
| gptkbp:domain |
DNA-binding domain
oligomerization domain transactivation domain |
| gptkbp:EC_number |
2.7.7.7
|
| gptkbp:encodedBy |
gptkb:TP53_gene
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSP00000269305
7157 |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
tumor suppressor
|
| gptkbp:GOProcess |
DNA repair
apoptotic process cell cycle arrest cellular response to stress |
| gptkbp:hasChromosomeLocation |
17p13.1
|
| gptkbp:hasDiseaseAssociation |
gptkb:Li-Fraumeni_syndrome
various cancers |
| gptkbp:hasGOFunction |
DNA-binding transcription factor activity
|
| gptkbp:hasIsoform |
P42773-1
P42773-10 P42773-11 P42773-12 P42773-13 P42773-14 P42773-15 P42773-16 P42773-17 P42773-18 P42773-19 P42773-2 P42773-20 P42773-21 P42773-22 P42773-23 P42773-24 P42773-25 P42773-26 P42773-27 P42773-28 P42773-29 P42773-3 P42773-30 P42773-31 P42773-32 P42773-33 P42773-34 P42773-35 P42773-36 P42773-37 P42773-38 P42773-39 P42773-4 P42773-40 P42773-41 P42773-42 P42773-43 P42773-44 P42773-45 P42773-46 P42773-47 P42773-48 P42773-49 P42773-5 P42773-50 P42773-6 P42773-7 P42773-8 P42773-9 |
| gptkbp:hasRefSeqID |
NP_000537.3
|
| gptkbp:hasUniProtEntryName |
gptkb:P53_HUMAN
|
| https://www.w3.org/2000/01/rdf-schema#label |
P42773
|
| gptkbp:length |
393 amino acids
|
| gptkbp:molecularWeight |
43.7 kDa
|
| gptkbp:numberInSeries |
MEEPQSDPSV...
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:pathway |
apoptosis
cell cycle p53 signaling pathway |
| gptkbp:PDB |
gptkb:2OCJ
gptkb:3KMD gptkb:4HJE 1TUP 5XVK |
| gptkbp:postTranslationalModification |
phosphorylation
methylation sumoylation ubiquitination acetylation |
| gptkbp:proteinFamily |
gptkb:p53_family
|
| gptkbp:refersTo |
gptkb:Tumor_protein_p53_(human)
|
| gptkbp:reviewedBy |
true
|
| gptkbp:subcellularLocation |
gptkb:nucleus
gptkb:cytoplasm mitochondrion |
| gptkbp:bfsParent |
gptkb:CDKN2C
|
| gptkbp:bfsLayer |
7
|