p53 family

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:discoveredBy gptkb:David_Lane
gptkbp:domain DNA-binding domain
oligomerization domain
transactivation domain
gptkbp:foundIn vertebrates
gptkbp:function regulation of cell cycle
tumor suppression
apoptosis regulation
https://www.w3.org/2000/01/rdf-schema#label p53 family
gptkbp:includes gptkb:p63
gptkb:p73
gptkb:p53
gptkbp:memberOf transcription factors
gptkbp:mutationAssociatedWith gptkb:cancer
gptkbp:proteinFamily TP53 family
gptkbp:regulates cell differentiation
DNA repair
senescence
cellular stress response
gptkbp:relatedTo cancer biology
gptkbp:bfsParent gptkb:p73
gptkb:HGNC:11762
gptkb:P18146
gptkb:HGNC:12362
gptkb:HGNC:12363
gptkb:TP63_gene
gptkb:Tumor_protein_p63
gptkbp:bfsLayer 7