|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:LDH-A
gptkb:Cell_proliferation-inducing_gene_19_protein
gptkb:LDH_muscle_subunit
|
|
gptkbp:associatedWith
|
gptkb:LDHA_deficiency
|
|
gptkbp:cofactor
|
NAD+
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000330708
3939
|
|
gptkbp:enzymeCommissionNumber
|
1.1.1.27
|
|
gptkbp:evidence_at_protein_level
|
yes
|
|
gptkbp:fullName
|
gptkb:L-lactate_dehydrogenase_A_chain
|
|
gptkbp:function
|
catalyzes the conversion of pyruvate to lactate with concomitant interconversion of NADH and NAD+
|
|
gptkbp:gene
|
gptkb:LDHA
gptkb:GCID:GC11P018191
|
|
gptkbp:hasIsoform
|
1
|
|
gptkbp:HGNC_ID
|
6541
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P00338 (human LDHA)
|
|
gptkbp:KEGGID
|
gptkb:hsa:3939
|
|
gptkbp:length
|
332 amino acids
|
|
gptkbp:locatedOnChromosome
|
11p15.4
chromosome 11: 18,191,858-18,200,228 (GRCh38)
|
|
gptkbp:molecularWeight
|
36,500 Da
|
|
gptkbp:OMIM
|
150000
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:pyruvate_metabolism
glycolysis
|
|
gptkbp:PDB
|
gptkb:1LLD
gptkb:4AJP
1I0Z
1I10
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
succinylation
|
|
gptkbp:Reactome
|
gptkb:R-HSA-70263
|
|
gptkbp:RefSeq
|
gptkb:NP_005557.1
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:structure
|
homotetramer
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
|
|
gptkbp:tissue_specificity
|
gptkb:skeletal_muscle
gptkb:kidney
gptkb:testis
heart
liver
erythrocyte
|
|
gptkbp:UniProt_entry_name
|
gptkb:LDHA_HUMAN
|
|
gptkbp:UniProtID
|
gptkb:P00338
|
|
gptkbp:bfsParent
|
gptkb:lactate_dehydrogenase
|
|
gptkbp:bfsLayer
|
6
|