|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:COX2
Cytochrome c oxidase polypeptide II
|
|
gptkbp:component
|
Cytochrome c oxidase complex
|
|
gptkbp:encodedBy
|
gptkb:MT-CO2
|
|
gptkbp:Entrez_Gene_ID
|
4513
|
|
gptkbp:enzymeCommissionNumber
|
1.9.3.1
|
|
gptkbp:function
|
Electron transfer in mitochondrial respiratory chain
|
|
gptkbp:GO
|
gptkb:GO:0008137
gptkb:GO:0004129
gptkb:GO:0005739
GO:0005743
GO:0006119
GO:0045275
GO:0045277
|
|
gptkbp:hasDiseaseAssociation
|
gptkb:Leigh_syndrome
cardiomyopathy
Mitochondrial complex IV deficiency
|
|
gptkbp:hasEnsembl
|
ENSG00000198712
|
|
gptkbp:hasPfam
|
PF00116
|
|
gptkbp:hasReactome
|
R-HSA-163200
|
|
gptkbp:hasRefSeqID
|
NP_001859.1
|
|
gptkbp:hasSubunitInteraction
|
Interacts with cytochrome c oxidase subunit 1
Interacts with cytochrome c oxidase subunit 3
|
|
gptkbp:HGNC_ID
|
7412
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P00338
|
|
gptkbp:InterPro
|
IPR002429
|
|
gptkbp:isEssential
|
true
|
|
gptkbp:isMitochondrial
|
true
|
|
gptkbp:KEGGID
|
hsa:4513
|
|
gptkbp:length
|
227 amino acids
|
|
gptkbp:locatedOnChromosome
|
MT
Mitochondrial DNA
|
|
gptkbp:molecularWeight
|
25,603 Da
|
|
gptkbp:OMIM
|
516040
|
|
gptkbp:organism
|
gptkb:Bos_taurus
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:5B1A
1OCC
2OCC
|
|
gptkbp:postTranslationalModification
|
Phosphorylation
Acetylation
|
|
gptkbp:reviewedBy
|
true
|
|
gptkbp:subcellularLocation
|
gptkb:Mitochondrion_inner_membrane
|
|
gptkbp:UniProt_entry_name
|
Cytochrome c oxidase subunit 2
|
|
gptkbp:UniProtID
|
gptkb:P00338
|
|
gptkbp:bfsParent
|
gptkb:EC_1.1.1.27
gptkb:1I10_(human_LDHA)
gptkb:LDH-A
gptkb:LDHA
gptkb:P00338_(human_LDHA)
|
|
gptkbp:bfsLayer
|
7
|