Statements (102)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
superfamily
|
| gptkbp:alsoKnownAs |
P-loop containing nucleoside triphosphate hydrolases
|
| gptkbp:catalyzes |
hydrolysis of NTPs
|
| gptkbp:example |
gptkb:EF-Tu
gptkb:Elongation_factor_Tu gptkb:G-proteins gptkb:RecA_protein gptkb:Ras_protein gptkb:Msh2 gptkb:Msh6 gptkb:Dynamin gptkb:ClpX gptkb:Hsp70 gptkb:MinD RuvB F1-ATPase ABC transporter proteins DnaA DnaB helicase Elongation factor G Elongation factor Ts FtsZ Gyrase Initiation factor 1 Initiation factor 2 Initiation factor 3 Kinesin MCM helicase Msh1 Msh10 Msh11 Msh12 Msh13 Msh14 Msh15 Msh16 Msh17 Msh18 Msh19 Msh20 Msh21 Msh22 Msh23 Msh24 Msh25 Msh26 Msh27 Msh28 Msh29 Msh3 Msh30 Msh31 Msh32 Msh33 Msh34 Msh35 Msh36 Msh37 Msh38 Msh39 Msh4 Msh40 Msh5 Msh7 Msh8 Msh9 MutS Myosin Rad51 RadA RecBCD Rho factor SRP54 SecA SecYEG translocon |
| gptkbp:firstDescribed |
1980s
|
| gptkbp:foundIn |
all domains of life
|
| gptkbp:function |
GTP binding
ATP binding bind and hydrolyze nucleoside triphosphates nucleoside-triphosphatase activity |
| https://www.w3.org/2000/01/rdf-schema#label |
P-loop NTPases
|
| gptkbp:includes |
gptkb:AAA+_proteins
gptkb:ABC_transporters gptkb:ATPases gptkb:helicases gptkb:kinases GTPases |
| gptkbp:InterProEntry |
gptkb:IPR027417
|
| gptkbp:motif |
P-loop motif
|
| gptkbp:motifSequence |
GxxxxGK[S/T]
|
| gptkbp:mutationAssociatedWith |
can cause disease
|
| gptkbp:PfamFamily |
gptkb:PF00025
|
| gptkbp:prositeEntry |
PS00842
|
| gptkbp:requires |
signal transduction
cell division protein synthesis cellular energy metabolism transport processes |
| gptkbp:structure |
gptkb:Rossmann_fold
|
| gptkbp:bfsParent |
gptkb:G3_motif
|
| gptkbp:bfsLayer |
7
|