Elongation factor Tu

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abundance one of the most abundant proteins in E. coli
gptkbp:alternativeName gptkb:EF-Tu
gptkb:elongation_factor_thermo_unstable
Tu factor
gptkbp:binds gptkb:GDP
gptkb:GTP
aminoacyl-tRNA
gptkbp:conservedIn prokaryotes
gptkbp:discoveredBy gptkb:Masayasu_Nomura
gptkbp:discoveredIn 1960s
gptkbp:EC_number 3.6.5.3
gptkbp:encodedBy gptkb:tuf_gene
gptkbp:family gptkb:GTP-binding_elongation_factors
gptkbp:foundIn gptkb:Bacteria
gptkbp:function guanine nucleotide exchange factor
translation elongation
gptkbp:gene gptkb:tufA
gptkb:tufB
gptkbp:GO GO:0003746
https://www.w3.org/2000/01/rdf-schema#label Elongation factor Tu
gptkbp:hydrolyzes gptkb:GTP
gptkbp:inhibitedBy gptkb:efrotomycin
gptkb:pulvomycin
gptkb:enacyloxin_IIa
gptkb:kirromycin
GE2270A
gptkbp:interactsWith ribosome
gptkbp:involvedIn protein biosynthesis
gptkbp:locatedOnChromosome bacterial chromosome
gptkbp:molecularWeight 43 kDa
gptkbp:mutationAssociatedWith lethal
gptkbp:numberOfGenesInEColi 2
gptkbp:organism gptkb:Bacteria
gptkbp:orthologIn gptkb:archaeal_aEF1A
gptkb:eukaryotic_eEF1A
gptkb:eEF1A
gptkbp:PDB gptkb:1EFC
gptkbp:postTranslationalModification phosphorylation
lysine methylation
gptkbp:releasesFromRibosome after GTP hydrolysis
gptkbp:releaseYear aminoacyl-tRNA
gptkbp:requires cell viability
gptkbp:role delivers aminoacyl-tRNA to ribosome
gptkbp:sequence highly conserved
gptkbp:structure three domains
gptkbp:subcellularLocation gptkb:cytoplasm
gptkbp:UniProtID gptkb:P0A6F5
gptkbp:bfsParent gptkb:EC_3.6.5.2
gptkbp:bfsLayer 6