helicases

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName nucleic acid helicase
gptkbp:EC_number 3.6.4.12
gptkbp:example gptkb:RecQ_helicase
gptkb:MCM_complex
DnaB helicase
NS3 helicase
XPD helicase
gptkbp:foundIn all domains of life
gptkbp:function unwind DNA or RNA
https://www.w3.org/2000/01/rdf-schema#label helicases
gptkbp:involvedIn DNA repair
transcription
DNA replication
recombination
RNA splicing
gptkbp:mechanismOfAction break hydrogen bonds between nucleic acid strands
gptkbp:mutationAssociatedWith gptkb:Rothmund-Thomson_syndrome
gptkb:Werner_syndrome
gptkb:Bloom_syndrome
genetic disorders
gptkbp:requires gptkb:ATP
gptkbp:studiedIn biochemistry
genetics
molecular biology
gptkbp:subclassOf nucleic acid binding protein
motor protein
gptkbp:bfsParent gptkb:P-loop_NTPase_superfamily
gptkb:Walker_A_motif
gptkb:P-loop
gptkbp:bfsLayer 7