|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
LexA autocleavage
|
|
gptkbp:alternativeName
|
DNA strand exchange protein RecA
recombinase A
|
|
gptkbp:binds
|
gptkb:ATP
single-stranded DNA
|
|
gptkbp:catalyzes
|
strand exchange
|
|
gptkbp:discoveredBy
|
gptkb:James_Clark
|
|
gptkbp:discoveredIn
|
1970
|
|
gptkbp:encodedBy
|
gptkb:recA_gene
|
|
gptkbp:form
|
nucleoprotein filament
|
|
gptkbp:foundIn
|
gptkb:Bacteria
|
|
gptkbp:function
|
DNA repair
homologous recombination
|
|
gptkbp:gene
|
recA
|
|
gptkbp:GO
|
GO:0006310
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RecA protein
|
|
gptkbp:inhibitedBy
|
LexA repressor
|
|
gptkbp:interactsWith
|
gptkb:LexA_protein
SSB protein
RecBCD complex
RecFOR complex
|
|
gptkbp:involvedIn
|
DNA damage response
|
|
gptkbp:locatedOnChromosome
|
E. coli 2,800,000-2,801,000 bp
|
|
gptkbp:molecularWeight
|
38 kDa
|
|
gptkbp:mutationAssociatedWith
|
increased sensitivity to DNA damage
defective recombination
impaired SOS response
|
|
gptkbp:orthologIn
|
Dmc1
Rad51
|
|
gptkbp:PDB
|
2REB
|
|
gptkbp:presentIn
|
gptkb:Bacteria
archaea
some eukaryotes
|
|
gptkbp:regulates
|
gptkb:SOS_response
|
|
gptkbp:requires
|
genome stability
genetic recombination
DNA repair by homologous recombination
prophage induction
|
|
gptkbp:reviewedBy
|
gptkb:Nature_Reviews_Molecular_Cell_Biology
gptkb:Annual_Review_of_Genetics
|
|
gptkbp:structure
|
filamentous
|
|
gptkbp:UniProtID
|
P0A7G6
|
|
gptkbp:bfsParent
|
gptkb:SOS_response
|
|
gptkbp:bfsLayer
|
7
|