|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:GTBP
gptkb:hMSH6
G/T mismatch-binding protein
|
|
gptkbp:associatedWith
|
gptkb:endometrial_cancer
colorectal cancer
|
|
gptkbp:biologicalProcess
|
DNA repair
mismatch repair
ATP binding
DNA binding
|
|
gptkbp:complex_name
|
MutSĪ±
|
|
gptkbp:discoveredBy
|
1995
|
|
gptkbp:Entrez_Gene_ID
|
2956
ENSG00000116062
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:formsComplexWith
|
gptkb:MSH2
|
|
gptkbp:fullName
|
gptkb:MutS_homolog_6
|
|
gptkbp:function
|
DNA mismatch repair
|
|
gptkbp:gene
|
gptkb:MSH6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Msh6
|
|
gptkbp:interactsWith
|
gptkb:MSH2
gptkb:PCNA
|
|
gptkbp:length
|
1360
|
|
gptkbp:locatedOnChromosome
|
chromosome 2p16.3
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:molecularWeight
|
160 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Lynch_syndrome
gptkb:hereditary_nonpolyposis_colorectal_cancer
nonsense
missense
frameshift
splice site
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Msh6
|
|
gptkbp:orthologInYeast
|
gptkb:MSH6
|
|
gptkbp:PDB
|
2O8B
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:proteinFamily
|
gptkb:MutS_family
|
|
gptkbp:RefSeq
|
NM_000179
|
|
gptkbp:reviewedBy
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:UniProt
OMIM:600678
|
|
gptkbp:UniProtID
|
P52701
|
|
gptkbp:bfsParent
|
gptkb:MSH6
|
|
gptkbp:bfsLayer
|
6
|