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gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:class
|
ABC transporter ATPase
F-type ATPase
P-type ATPase
V-type ATPase
|
|
gptkbp:cofactor
|
Mg2+
|
|
gptkbp:discoveredBy
|
gptkb:Jens_Christian_Skou
|
|
gptkbp:discoveredIn
|
1957
|
|
gptkbp:EC_number
|
3.6.1.3
|
|
gptkbp:example
|
Ca2+-ATPase
F-ATPase
H+/K+-ATPase
Na+/K+-ATPase
V-ATPase
dynein ATPase
kinesin ATPase
myosin ATPase
|
|
gptkbp:foundIn
|
all domains of life
|
|
gptkbp:function
|
catalyze hydrolysis of ATP
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ATPases
|
|
gptkbp:importantFor
|
cellular homeostasis
intracellular transport
membrane potential maintenance
|
|
gptkbp:inhibitedBy
|
gptkb:ouabain
vanadate
|
|
gptkbp:mechanismOfAction
|
nucleophilic attack on gamma phosphate
|
|
gptkbp:powerSource
|
ATP hydrolysis
|
|
gptkbp:product
|
gptkb:adenosine_diphosphate
inorganic phosphate
|
|
gptkbp:role
|
muscle contraction
active transport
cell motility
ion transport
energy transduction
|
|
gptkbp:substrate
|
gptkb:adenosine_triphosphate
|
|
gptkbp:bfsParent
|
gptkb:P-loop_NTPase_superfamily
gptkb:CHEBI:28009
gptkb:Walker_A_motif
gptkb:CHEBI:17580
gptkb:P-loop
|
|
gptkbp:bfsLayer
|
7
|