Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
tumor suppressor |
| gptkbp:alias |
gptkb:NRAS
gptkb:C-K-N-RAS gptkb:N-ras gptkb:Neuroblastoma_RAS_viral_oncogene_homolog |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:acute_myeloid_leukemia colorectal cancer melanoma thyroid carcinoma |
| gptkbp:chromosomeArm |
1p13.2
|
| gptkbp:discoveredBy |
gptkb:Robin_Weiss
|
| gptkbp:discoveredIn |
1983
|
| gptkbp:encodes |
gptkb:NRAS_protein
|
| gptkbp:Entrez_Gene_ID |
4893
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
signal transduction
GTPase activity |
| gptkbp:HGNC_ID |
7989
|
| https://www.w3.org/2000/01/rdf-schema#label |
NRAS proto-oncogene
|
| gptkbp:locatedOnChromosome |
chromosome 1
|
| gptkbp:mutationAssociatedWith |
germline mutation
somatic mutation |
| gptkbp:OMIM |
164790
|
| gptkbp:orthologInMouse |
gptkb:Nras
|
| gptkbp:orthologInZebrafish |
nras
|
| gptkbp:proteinFamily |
gptkb:RAS_family
|
| gptkbp:regulates |
apoptosis
cell differentiation cell proliferation |
| gptkbp:UniProtID |
gptkb:P01111
|
| gptkbp:bfsParent |
gptkb:Nras
gptkb:human_NRAS |
| gptkbp:bfsLayer |
6
|