|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
hereditary breast and ovarian cancer
|
|
gptkbp:biologicalProcess
|
gptkb:cell_cycle_checkpoint
ubiquitin-protein transferase activity
DNA binding
double-strand break repair
homologous recombination
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
|
|
gptkbp:domain
|
gptkb:BRCT_domain
RING finger domain
coiled-coil domain
|
|
gptkbp:encodedBy
|
gptkb:BRCA1_gene
|
|
gptkbp:Entrez_Gene_ID
|
672
|
|
gptkbp:function
|
DNA repair
tumor suppression
|
|
gptkbp:hasIsoform
|
gptkb:BRCA1_protein
|
|
gptkbp:interactsWith
|
gptkb:CtIP
gptkb:BARD1
gptkb:PALB2
gptkb:RAD51
|
|
gptkbp:length
|
1863 amino acids
|
|
gptkbp:locatedOnChromosome
|
17q21.31
|
|
gptkbp:mass
|
207 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1JM7
gptkb:1T15
gptkb:4IGK
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:refersTo
|
BRCA1 protein isoform 1
|
|
gptkbp:RefSeq
|
gptkb:NP_000066
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:UniProtID
|
P38398
ENSP00000350283
|
|
gptkbp:bfsParent
|
gptkb:NM_000075
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NP 000066
|