|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:GIF
gptkb:L-dopachrome_isomerase
gptkb:phenylpyruvate_tautomerase
glycosylation-inhibiting factor
|
|
gptkbp:associatedWith
|
gptkb:cancer
asthma
sepsis
autoimmune diseases
rheumatoid arthritis
|
|
gptkbp:discoveredBy
|
gptkb:John_David
|
|
gptkbp:discoveredIn
|
1966
|
|
gptkbp:encodedBy
|
gptkb:MIF_gene
|
|
gptkbp:expressedIn
|
gptkb:pituitary_gland
gptkb:T_cells
various tissues
macrophages
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkb:Rattus_norvegicus
|
|
gptkbp:fullName
|
gptkb:Macrophage_Migration_Inhibitory_Factor
|
|
gptkbp:function
|
cytokine
regulation of immune response
inhibition of macrophage migration
|
|
gptkbp:gene
|
gptkb:MIF
|
|
gptkbp:hasBiologicalActivity
|
tautomerase
|
|
gptkbp:hasReceptor
|
gptkb:CD74
gptkb:CXCR2
gptkb:CXCR4
gptkb:CXCR7
|
|
gptkbp:HGNC_ID
|
7097
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MIF
|
|
gptkbp:involvedIn
|
immune system regulation
inflammatory response
|
|
gptkbp:locatedOnChromosome
|
22q11.23
|
|
gptkbp:molecularWeight
|
12.5 kDa
|
|
gptkbp:OMIM
|
153620
|
|
gptkbp:orthologInMouse
|
gptkb:Mif
|
|
gptkbp:PDB
|
1MFI
|
|
gptkbp:regulates
|
gptkb:p53
apoptosis
cell proliferation
angiogenesis
oxidative stress response
glucocorticoid action
inflammatory cytokine production
|
|
gptkbp:structure
|
homotrimer
|
|
gptkbp:UniProtID
|
P14174
|
|
gptkbp:bfsParent
|
gptkb:Malmö_Redhawks
gptkb:Multilateral_Investment_Fund
gptkb:MapInfo_Professional
|
|
gptkbp:bfsLayer
|
6
|