Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:Cluster_of_Differentiation_74
gptkb:HLA_class_II_histocompatibility_antigen_gamma_chain |
| gptkbp:encodedBy |
gptkb:CD74_gene
|
| gptkbp:Entrez_Gene_ID |
972
|
| gptkbp:expressedIn |
gptkb:B_cells
dendritic cells monocytes some epithelial cells |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
gptkb:MHC_class_II_chaperone
antigen presentation regulation of immune response |
| https://www.w3.org/2000/01/rdf-schema#label |
CD74
|
| gptkbp:interactsWith |
gptkb:macrophage_migration_inhibitory_factor_(MIF)
gptkb:MHC_class_II_molecules |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_5q32
|
| gptkbp:location |
cell surface
endosomal/lysosomal compartments |
| gptkbp:significance |
marker for certain lymphomas
target for immunotherapy |
| gptkbp:UniProtID |
gptkb:P04233
|
| gptkbp:bfsParent |
gptkb:MIF
|
| gptkbp:bfsLayer |
7
|