Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:actsOn |
gptkb:JNK
gptkb:p38_MAPK gptkb:ERK |
| gptkbp:alternativeName |
gptkb:DUSP
gptkb:dual_specificity_phosphatase |
| gptkbp:contains |
dual specificity phosphatase domain
|
| gptkbp:EC_number |
3.1.3.16
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
dephosphorylation of MAP kinases
|
| gptkbp:hasMember |
gptkb:DUSP1
gptkb:DUSP10 gptkb:DUSP16 gptkb:DUSP2 gptkb:DUSP4 gptkb:DUSP5 gptkb:DUSP6 gptkb:DUSP7 gptkb:DUSP8 gptkb:DUSP9 |
| https://www.w3.org/2000/01/rdf-schema#label |
MAPK phosphatase (DUSP)
|
| gptkbp:inhibitedBy |
MAPK activity
|
| gptkbp:involvedIn |
apoptosis regulation
cell proliferation regulation immune response regulation cellular response to stress |
| gptkbp:proteinFamily |
gptkb:DUSP
|
| gptkbp:regulates |
gptkb:MAPK_signaling_pathway
|
| gptkbp:substrate |
phosphorylated threonine
phosphorylated tyrosine |
| gptkbp:bfsParent |
gptkb:Negative_regulation_of_MAPK_pathway
|
| gptkbp:bfsLayer |
7
|