Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alias |
gptkb:MKP-5
gptkb:MKP5 HVH8 |
| gptkbp:associatedWith |
gptkb:cancer
inflammatory diseases |
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000139318
11221 |
| gptkbp:enzymeClassification |
gptkb:EC_3.1.3.16
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
gptkb:Dual_specificity_protein_phosphatase_10
|
| gptkbp:function |
dephosphorylates MAP kinases
regulates MAPK signaling pathways |
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
gptkb:DUSP10
|
| https://www.w3.org/2000/01/rdf-schema#label |
DUSP10
|
| gptkbp:inhibitedBy |
MAP kinase activity
|
| gptkbp:locatedOnChromosome |
1
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm 1q41 |
| gptkbp:molecularWeight |
~42 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Dusp10
|
| gptkbp:phosphatase_domain |
present
|
| gptkbp:regulates |
gptkb:p38_MAPK
gptkb:JNK_MAPK |
| gptkbp:substrate |
dual specificity (serine/threonine and tyrosine residues)
|
| gptkbp:UniProtID |
gptkb:Q13115
|
| gptkbp:bfsParent |
gptkb:DUSP
|
| gptkbp:bfsLayer |
6
|